RESEARCH

F.Groot, G.Jonker, M.Rinia, O.tenCate, and R.Hoff:
Simulation at the frontier of the Zone of Proximal Development: A test in acute care for inexperienced learners.
2020, Academic Medicine
[.pdf] [pubmed]


A.Baxter, R.Russell, C.Duncan, M.Moore, C.Willberg, J.Pablos, A.Finzi, D.Kaufmann, C.Ochsenbauer, J.Kappes, F.Groot*, Q.Sattentau* (*co-senior author):
Macrophage infection via selective capture of HIV-1-infected CD4+ T Cells.
2014, Cell Host & Microbe
[.pdf] [pubmed]


S.Welsch, F.Groot, H.Krausslich, O.Keppler, Q.Sattentau:
Architecture and regulation of the HIV-1 assembly and holding compartment in macrophages.
2011, Journal of Virology
[.pdf] [pubmed]


F.Groot, S.Welsch, Q.Sattentau:
Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses.
2008, Blood
[.pdf] [pubmed]


R.Sanders, E.vanAnken, A.Nabatov, M.Liscaljet, I.Bontjer, D.Eggink, M.Melchers, E.Busser, M.Dankers, F.Groot, I.Braakman, B.Berkhout, W.Paxton:
The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion.
2008, Retrovirology
[.pdf] [pubmed]


F.Groot:
Dendritic cell-mediated HIV-1 transmission.
2006, PhD thesis (ISBN: 90-8559-192-9)

[.pdf]


A.vanderKuyl, R.vandenBurg, F.Zorgdrager, F.Groot, B.Berkhout, M.Cornelissen:
Sialoadhesin (CD169) expression in CD14+ cells is upregulated early after HIV-1 infection and increases during disease progression.
2007, PLoS ONE
[.pdf] [pubmed]


F.Groot, T.vanCapel, M.Kapsenberg, B.Berkhout, E.deJong:
Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: transmission facilitation versus replication inhibition.
2006, Blood
[.pdf] [pubmed] [comment in blood journal]


F.Groot, T.Kuijpers, B.Berkhout, E.deJong:
Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1.
2006, Retrovirology
[.pdf] [pubmed]


F.Groot, T.vanCapel, J.Schuitemaker, B.Berkhout, E.deJong:
Differential susceptibility of nave, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission.
2006, Retrovirology
[.pdf] [pubmed]


F.Groot, R.Sanders, O.terBrake, K.Nazmi, E.Veerman, J.Bolscher, B.Berkhout:
Histatin 5-derived peptide with improved fungicidal properties enhances HIV-1 replication by promoting viral entry.
2006, Journal of Virology

[.pdf] [pubmed]


H.Schmidlin, W.Dontje, F.Groot, S.Ligthart, A.Colantonio, M.Oud, E.Schilder, M.Spaargaren, H.Spits, C.Uittenbogaart, B.Blom:
Stimulated plasmacytoid dendritic cells impair human T cell development.
2006, Blood

[.pdf] [pubmed]


M.Naarding, I.Ludwig, F.Groot, B.Berkhout, T.Geijtenbeek, G.Pollakis, W.Paxton:
Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T-lymphocytes.
2005, Journal of Clinical Investigation
[.pdf] [pubmed]


F.Groot, T.Geijtenbeek, R.Sanders, C.Baldwin, M.Sanchez-Hernandez, R.Floris, Y.vanKooyk, E.deJong, B.Berkhout:
Lactoferrin prevents dendritic cell-mediated HIV-1 transmission by blocking the DC-SIGNgp120 interaction.
2005, Journal of Virology
[.pdf] [pubmed]


N.Beerens, F.Groot, B.Berkhout:
Initiation of HIV-1 reverse transcription is regulated by a primer activation signal.
2001, Journal of Biological Chemistry
[.pdf] [pubmed]


N.Beerens, F.Groot, B.Berkhout:
Stabilization of the U5-leader stem in the HIV-1 RNA genome affects initiation and elongation of reverse transcription.
2000, Nucleic Acids Research
[.pdf] [pubmed]